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Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia
Influenza viruses (IV) cause pneumonia in humans with progression to lung failure and fatal outcome. Dysregulated release of cytokines including type I interferons (IFNs) has been attributed a crucial role in immune-mediated pulmonary injury during severe IV infection. Using ex vivo and in vivo IV i...
Autores principales: | Högner, Katrin, Wolff, Thorsten, Pleschka, Stephan, Plog, Stephanie, Gruber, Achim D., Kalinke, Ulrich, Walmrath, Hans-Dieter, Bodner, Johannes, Gattenlöhner, Stefan, Lewe-Schlosser, Peter, Matrosovich, Mikhail, Seeger, Werner, Lohmeyer, Juergen, Herold, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585175/ https://www.ncbi.nlm.nih.gov/pubmed/23468627 http://dx.doi.org/10.1371/journal.ppat.1003188 |
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