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MicroRNA-762 Is Upregulated in Human Corneal Epithelial Cells in Response to Tear Fluid and Pseudomonas aeruginosa Antigens and Negatively Regulates the Expression of Host Defense Genes Encoding RNase7 and ST2

Mucosal surfaces regulate defenses against infection and excessive inflammation. We previously showed that human tears upregulated epithelial expression of genes encoding RNase7 and ST2, which inhibited Pseudomonas aeruginosa invasion of human corneal epithelial cells. Here, microRNA microarrays wer...

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Detalles Bibliográficos
Autores principales: Mun, James, Tam, Connie, Chan, Gary, Kim, Jong Hun, Evans, David, Fleiszig, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585208/
https://www.ncbi.nlm.nih.gov/pubmed/23469087
http://dx.doi.org/10.1371/journal.pone.0057850