Cell-Type-Specific Predictive Network Yields Novel Insights into Mouse Embryonic Stem Cell Self-Renewal and Cell Fate

Self-renewal, the ability of a stem cell to divide repeatedly while maintaining an undifferentiated state, is a defining characteristic of all stem cells. Here, we clarify the molecular foundations of mouse embryonic stem cell (mESC) self-renewal by applying a proven Bayesian network machine learnin...

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Detalles Bibliográficos
Autores principales: Dowell, Karen G., Simons, Allen K., Wang, Zack Z., Yun, Kyuson, Hibbs, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585227/
https://www.ncbi.nlm.nih.gov/pubmed/23468881
http://dx.doi.org/10.1371/journal.pone.0056810

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