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Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

Insulin resistance (IR), an impaired cellular, tissue and whole body response to insulin, is a major pathophysiological defect of type 2 diabetes mellitus. Although IR is closely associated with obesity, the identity of the molecular defect(s) underlying obesity-induced IR in skeletal muscle remains...

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Detalles Bibliográficos
Autores principales:	Ruiz-Alcaraz, Antonio J., Lipina, Christopher, Petrie, John R., Murphy, Michael J., Morris, Andrew D., Sutherland, Calum, Cuthbertson, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585240/ https://www.ncbi.nlm.nih.gov/pubmed/23468892 http://dx.doi.org/10.1371/journal.pone.0056928

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