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Immunization with Cholera Toxin B Subunit Induces High-Level Protection in the Suckling Mouse Model of Cholera

Cholera toxin (CT) is the primary virulence factor responsible for severe cholera. Vibrio cholerae strains unable to produce CT show severe attenuation of virulence in animals and humans. The pentameric B subunit of CT (CTB) contains the immunodominant epitopes recognized by antibodies that neutrali...

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Detalles Bibliográficos
Autores principales:	Price, Gregory A., McFann, Kim, Holmes, Randall K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585264/ https://www.ncbi.nlm.nih.gov/pubmed/23468950 http://dx.doi.org/10.1371/journal.pone.0057269

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