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Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance
Rap1 and Rap2 are closely related proteins of the Ras family of small G-proteins. Rap1 is well known to regulate cell-cell adhesion. Here, we have analysed the effect of Rap-mediated signalling on endothelial permeability using electrical impedance measurements of HUVEC monolayers and subsequent det...
Autores principales: | Pannekoek, Willem-Jan, Linnemann, Jelena R., Brouwer, Patricia M., Bos, Johannes L., Rehmann, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585282/ https://www.ncbi.nlm.nih.gov/pubmed/23469100 http://dx.doi.org/10.1371/journal.pone.0057903 |
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