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Contribution of V(H) Replacement Products in Mouse Antibody Repertoire
V(H) replacement occurs through RAG-mediated recombination between the cryptic recombination signal sequence (cRSS) near the 3′ end of a rearranged V(H) gene and the 23-bp RSS from an upstream unrearranged V(H) gene. Due to the location of the cRSS, V(H) replacement leaves a short stretch of nucleot...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585286/ https://www.ncbi.nlm.nih.gov/pubmed/23469094 http://dx.doi.org/10.1371/journal.pone.0057877 |