Hyperglycemia: GDNF-EGR1 Pathway Target Renal Epithelial Cell Migration and Apoptosis in Diabetic Renal Embryopathy

Maternal hyperglycemia can inhibit morphogenesis of ureteric bud branching, Glial cell line-derived neurotrophilic factor (GDNF) is a key regulator of the initiation of ureteric branching. Early growth response gene-1 (EGR-1) is an immediate early gene. Preliminary study found EGR-1 persistently exp...

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Detalles Bibliográficos
Autores principales: Lin, Ching-Yuang, Lin, Tze-Yi, Lee, Min-Chun, Chen, Shih-Chieh, Chang, Jeng-Shou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585314/
https://www.ncbi.nlm.nih.gov/pubmed/23468876
http://dx.doi.org/10.1371/journal.pone.0056731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585314/
https://www.ncbi.nlm.nih.gov/pubmed/23468876
http://dx.doi.org/10.1371/journal.pone.0056731

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