Association of Thymidylate Synthase Polymorphisms with Acute Pancreatitis and/or Peripheral Neuropathy in HIV-Infected Patients on Stavudine-Based Therapy

BACKGROUND: Low expression thymidylate synthase (TS) polymorphism has been associated with increased stavudine triphosphate intracellular (d4T-TP) levels and the lipodystrophy syndrome. The use of d4T has been associated with acute pancreatitis and peripheral neuropathy. However, no relationship has...

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Detalles Bibliográficos
Autores principales: Domingo, Pere, Cabeza, Maria del Carmen, Torres, Ferran, Salazar, Juliana, Gutierrez, Maria del Mar, Mateo, Maria Gracia, Martínez, Esteban, Domingo, Joan Carles, Fernandez, Irene, Villarroya, Francesc, Ribera, Esteban, Vidal, Francesc, Baiget, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585348/
https://www.ncbi.nlm.nih.gov/pubmed/23468971
http://dx.doi.org/10.1371/journal.pone.0057347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585348/
https://www.ncbi.nlm.nih.gov/pubmed/23468971
http://dx.doi.org/10.1371/journal.pone.0057347

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