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Halogenation Generates Effective Modulators of Amyloid-Beta Aggregation and Neurotoxicity

Halogenation of organic compounds plays diverse roles in biochemistry, including selective chemical modification of proteins and improved oral absorption/blood-brain barrier permeability of drug candidates. Moreover, halogenation of aromatic molecules greatly affects aromatic interaction-mediated se...

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Detalles Bibliográficos
Autores principales:	Wong, H. Edward, Irwin, Jacob A., Kwon, Inchan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585355/ https://www.ncbi.nlm.nih.gov/pubmed/23468958 http://dx.doi.org/10.1371/journal.pone.0057288

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