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The HAMP Signal Relay Domain Adopts Multiple Conformational States through Collective Piston and Tilt Motions
The HAMP domain is a linker region in prokaryotic sensor proteins and relays input signals to the transmitter domain and vice versa. Functional as a dimer, the structure of HAMP shows a parallel coiled-coil motif comprising four helices. To date, it is unclear how HAMP can relay signals from one dom...
Autores principales: | Zhu, Lizhe, Bolhuis, Peter G., Vreede, Jocelyne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585426/ https://www.ncbi.nlm.nih.gov/pubmed/23468603 http://dx.doi.org/10.1371/journal.pcbi.1002913 |
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