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The HAMP Signal Relay Domain Adopts Multiple Conformational States through Collective Piston and Tilt Motions

The HAMP domain is a linker region in prokaryotic sensor proteins and relays input signals to the transmitter domain and vice versa. Functional as a dimer, the structure of HAMP shows a parallel coiled-coil motif comprising four helices. To date, it is unclear how HAMP can relay signals from one dom...

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Detalles Bibliográficos
Autores principales: Zhu, Lizhe, Bolhuis, Peter G., Vreede, Jocelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585426/
https://www.ncbi.nlm.nih.gov/pubmed/23468603
http://dx.doi.org/10.1371/journal.pcbi.1002913

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