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p110δ PI3 kinase pathway: emerging roles in cancer

Class IA PI3Ks consists of three isoforms of the p110 catalytic subunit designated p110α, p110β, and p110δ which are encoded by three separate genes. Gain-of-function mutations on PIK3CA gene encoding for p110α isoform have been detected in a wide variety of human cancers whereas no somatic mutation...

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Detalles Bibliográficos
Autores principales:	Tzenaki, Niki, Papakonstanti, Evangelia A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585436/ https://www.ncbi.nlm.nih.gov/pubmed/23459844 http://dx.doi.org/10.3389/fonc.2013.00040

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