Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency

How cell fate becomes restricted during somatic cell differentiation is a long-lasting question in biology. Epigenetic mechanisms not present in pluripotent cells and acquired during embryonic development are expected to stabilize the differentiated state of somatic cells and thereby restrict their...

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Detalles Bibliográficos
Autores principales: Pasque, Vincent, Radzisheuskaya, Aliaksandra, Gillich, Astrid, Halley-Stott, Richard P., Panamarova, Maryna, Zernicka-Goetz, Magdalena, Surani, M. Azim, Silva, José C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585521/
https://www.ncbi.nlm.nih.gov/pubmed/23077180
http://dx.doi.org/10.1242/jcs.113019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585521/
https://www.ncbi.nlm.nih.gov/pubmed/23077180
http://dx.doi.org/10.1242/jcs.113019

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