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Effect of Food on the Pharmacokinetic Profile of Etamicastat (BIA 5-453)

Background: Etamicastat is a novel, potent, and reversible peripheral dopamine-β-hydroxylase inhibitor that has been administered orally at doses up to 600mg once daily for 10 days to male healthy volunteers and appears to be well tolerated. Objective: The aim of this study was to investigate the ef...

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Detalles Bibliográficos
Autores principales: Vaz-da-Silva, Manuel, Nunes, Teresa, Rocha, José F., Falcão, Amilcar, Almeida, Luis, Soares-da-Silval, Patricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585837/
https://www.ncbi.nlm.nih.gov/pubmed/21548660
http://dx.doi.org/10.2165/11587080-000000000-00000