Cargando…

Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression

Pathology studies of progressive multiple sclerosis (MS) indicate a major role of inflammation including Th17-cells and meningeal inflammation with ectopic lymphoid follicles, B-cells and plasma cells, the latter indicating a possible role of the newly identified subset of follicular T-helper (T(FH)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Christensen, Jeppe Romme, Börnsen, Lars, Ratzer, Rikke, Piehl, Fredrik, Khademi, Mohsen, Olsson, Tomas, Sørensen, Per Soelberg, Sellebjerg, Finn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585852/ https://www.ncbi.nlm.nih.gov/pubmed/23469245 http://dx.doi.org/10.1371/journal.pone.0057820

Ejemplares similares

Correction: Systemic Inflammation in Progressive Multiple Sclerosis Involves Follicular T-Helper, Th17- and Activated B-Cells and Correlates with Progression
por: Romme Christensen, Jeppe, et al.
Publicado: (2013)

Progressive multiple sclerosis, cognitive function, and quality of life
por: Højsgaard Chow, Helene, et al.
Publicado: (2018)

Effect of Natalizumab on Circulating CD4(+) T-Cells in Multiple Sclerosis
por: Börnsen, Lars, et al.
Publicado: (2012)

Absence of systemic oxidative stress and increased CSF prostaglandin F(2α) in progressive MS
por: Lam, Magda A., et al.
Publicado: (2016)

Cellular sources of dysregulated cytokines in relapsing-remitting multiple sclerosis
por: Romme Christensen, Jeppe, et al.
Publicado: (2012)

Endogenous Interferon-β-Inducible Gene Expression and Interferon-β-Treatment Are Associated with Reduced T Cell Responses to Myelin Basic Protein in Multiple Sclerosis
por: Börnsen, Lars, et al.
Publicado: (2015)

Lipocalin-2 is increased in progressive multiple sclerosis and inhibits remyelination
por: Al Nimer, Faiez, et al.
Publicado: (2016)

Pregnancy-Induced Changes in microRNA Expression in Multiple Sclerosis
por: Søndergaard, Helle Bach, et al.
Publicado: (2021)

Transcriptome and Function of Novel Immunosuppressive Autoreactive Invariant Natural Killer T Cells That Are Absent in Progressive Multiple Sclerosis
por: Carrión, Belinda, et al.
Publicado: (2021)

Dimethyl Fumarate Treatment in Patients With Primary Progressive Multiple Sclerosis: A Randomized, Controlled Trial
por: Højsgaard Chow, Helene, et al.
Publicado: (2021)

Pulsed immune reconstitution therapy in multiple sclerosis
por: Sorensen, Per Soelberg, et al.
Publicado: (2019)

Increased Intrathecal Activity of Follicular Helper T Cells in Patients With Relapsing-Remitting Multiple Sclerosis
por: Holm Hansen, Rikke, et al.
Publicado: (2022)

Imaging cortical multiple sclerosis lesions with ultra-high field MRI
por: Madsen, Mads A.J., et al.
Publicado: (2021)

Systemic frequencies of T helper 1 and T helper 17 cells in patients with age-related macular degeneration: A case-control study
por: Singh, Amardeep, et al.
Publicado: (2017)

The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis
por: Iacobaeus, Ellen, et al.
Publicado: (2011)

Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis
por: Nielsen, Claus H., et al.
Publicado: (2016)

Endogenous and Recombinant Type I Interferons and Disease Activity in Multiple Sclerosis
por: Sellebjerg, Finn, et al.
Publicado: (2012)

Follicular helper T cells progressively differentiate to regulate the germinal center response
por: Weinstein, Jason S., et al.
Publicado: (2016)

Recovery from an acute relapse is associated with changes in motor resting-state connectivity in multiple sclerosis
por: Dogonowski, Anne-Marie, et al.
Publicado: (2016)

GM-CSF and CXCR4 Define a T Helper Cell Signature in Multiple Sclerosis
por: Galli, Edoardo, et al.
Publicado: (2019)

T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance
por: Gao, Xin, et al.
Publicado: (2023)

Linking lesions in sensorimotor cortex to contralateral hand function in multiple sclerosis: a 7 T MRI study
por: Madsen, Mads A J, et al.
Publicado: (2022)

Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis
por: Bergman, Petra, et al.
Publicado: (2016)

Intrathecal CD8(+)CD20(+) T Cells in Primary Progressive Multiple Sclerosis
por: von Essen, Marina Rode, et al.
Publicado: (2023)

The Frequency of Intrathyroidal Follicular Helper T Cells Varies with the Progression of Graves' Disease and Hashimoto's Thyroiditis
por: Cai, Yun, et al.
Publicado: (2022)

Impaired Function of CD4+ T Follicular Helper (Tfh) Cells Associated with Hepatocellular Carcinoma Progression
por: Jia, Yiqiong, et al.
Publicado: (2015)

Artemisinin analogue SM934 attenuate collagen-induced arthritis by suppressing T follicular helper cells and T helper 17 cells
por: Lin, Ze-Min, et al.
Publicado: (2016)

Life of T Follicular Helper Cells
por: Suh, Woong-Kyung
Publicado: (2015)

Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers
por: Huang, Jesse, et al.
Publicado: (2021)

Decreased Expression of Negative Immune Checkpoint VISTA by CD4+ T Cells Facilitates T Helper 1, T Helper 17, and T Follicular Helper Lineage Differentiation in GCA
por: Hid Cadena, Rebeca, et al.
Publicado: (2019)

Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis
por: Marshall, Erin A., et al.
Publicado: (2016)

Comorbidity in Multiple Sclerosis
por: Magyari, Melinda, et al.
Publicado: (2020)

Inflammatory vaginitis associated with long-term rituximab treatment in a patient with multiple sclerosis
por: Filikci, Zuhal, et al.
Publicado: (2022)

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells
por: Ritvo, Paul-Gydéon, et al.
Publicado: (2019)

T follicular helper cells and T follicular regulatory cells in autoimmune diseases
por: Qi, Jingjing, et al.
Publicado: (2023)

Regulation of T follicular helper cells by ICOS
por: Hutloff, Andreas
Publicado: (2015)

Follicular helper T cell in immunity and autoimmunity
por: Mesquita, D., et al.
Publicado: (2016)

T Follicular Helper Cells in Autoimmune Disorders
por: Gensous, Noémie, et al.
Publicado: (2018)

Primary cutaneous T‐follicular helper lymphoma
por: Fenu, Elena M., et al.
Publicado: (2023)

Inflammation-related plasma and CSF biomarkers for multiple sclerosis
por: Huang, Jesse, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0uv53mnilbsdm5ponk1kk9bslf