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Targeting early B-cell receptor signaling induces apoptosis in leukemic mantle cell lymphoma

BACKGROUND: We previously showed that B-cell receptor (BCR) signaling pathways are important for in vitro survival of mantle cell lymphoma (MCL) cells. To further identify early BCR-activated signaling pathways involved in MCL cell survival, we focused our study on BCR-proximal kinases such as LYN w...

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Detalles Bibliográficos
Autores principales: Boukhiar, Mohand-Akli, Roger, Claudine, Tran, Julie, Gressin, Remy, Martin, Antoine, Ajchenbaum-Cymbalista, Florence, Varin-Blank, Nadine, Ledoux, Dominique, Baran-Marszak, Fanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585857/
https://www.ncbi.nlm.nih.gov/pubmed/23422267
http://dx.doi.org/10.1186/2162-3619-2-4