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Defective alterations in the collagen network to prostacyclin in COPD lung fibroblasts

BACKGROUND: Prostacyclin analogs are potent vasodilators and possess anti-inflammatory properties. However, the effect of prostacyclin on extracellular matrix (ECM) in COPD is not well known. Collagen fibrils and proteoglycans are essential ECM components in the lung and fibroblasts are key players...

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Detalles Bibliográficos
Autores principales:	Larsson-Callerfelt, Anna-Karin, Hallgren, Oskar, Andersson-Sjöland, Annika, Thiman, Lena, Björklund, Johan, Kron, Josefine, Nihlberg, Kristian, Bjermer, Leif, Löfdahl, Claes-Göran, Westergren-Thorsson, Gunilla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585859/ https://www.ncbi.nlm.nih.gov/pubmed/23406566 http://dx.doi.org/10.1186/1465-9921-14-21

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