Catalytic and Functional Roles of Conserved Amino Acids in the SET Domain of the S. cerevisiae Lysine Methyltransferase Set1

In S. cerevisiae, the lysine methyltransferase Set1 is a member of the multiprotein complex COMPASS. Set1 catalyzes mono-, di- and trimethylation of the fourth residue, lysine 4, of histone H3 using methyl groups from S-adenosylmethionine, and requires a subset of COMPASS proteins for this activity....

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Detalles Bibliográficos
Autores principales: Williamson, Kelly, Schneider, Victoria, Jordan, Rachel A., Mueller, John E., Henderson Pozzi, Michelle, Bryk, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585878/
https://www.ncbi.nlm.nih.gov/pubmed/23469257
http://dx.doi.org/10.1371/journal.pone.0057974

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