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Increased Artemis levels confer radioresistance to both high and low LET radiation exposures
BACKGROUND: Artemis has a defined role in V(D)J recombination and has been implicated in the repair of radiation induced double-strand breaks. However the exact function(s) of Artemis in DNA repair and its preferred substrate(s) in vivo remain undefined. Our previous work suggests that Artemis is im...
Autores principales: | Sridharan, Deepa M, Whalen, Mary K, Almendrala, Donna, Cucinotta, Francis A, Kawahara, Misako, Yannone, Steven M, Pluth, Janice M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585927/ https://www.ncbi.nlm.nih.gov/pubmed/22713703 http://dx.doi.org/10.1186/1748-717X-7-96 |
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