Robustness and Backbone Motif of a Cancer Network Regulated by miR-17-92 Cluster during the G1/S Transition

Based on interactions among transcription factors, oncogenes, tumor suppressors and microRNAs, a Boolean model of cancer network regulated by miR-17-92 cluster is constructed, and the network is associated with the control of G1/S transition in the mammalian cell cycle. The robustness properties of...

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Detalles Bibliográficos
Autores principales: Yang, Lijian, Meng, Yan, Bao, Chun, Liu, Wangheng, Ma, Chengzhang, Li, Anbang, Xuan, Zhan, Shan, Ge, Jia, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585929/
https://www.ncbi.nlm.nih.gov/pubmed/23469179
http://dx.doi.org/10.1371/journal.pone.0057009

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