Pharmacokinetics, Safety and Tolerability of Bencycloquidium Bromide, a Novel Selective Muscarinic M1/M3 Receptor Antagonist, After Single and Multiple Intranasal Doses in Healthy Chinese Subjects: An Open-Label, Single-Center, First-in-Human Study

Background: Bencycloquidium bromide (BCQB) is a novel, potent and selective muscarinic M1/M3 receptor antagonist under development for the treatment of rhinorrhea in rhinitis. The pharmacokinetics and safety of BCQB in animals have been established in preclinical studies. However, no clinical pharma...

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Detalles Bibliográficos
Autores principales: Sun, Luning, Ding, Li, Wang, Yongqing, Zhou, Wenjia, Yan, Zhengyu, Sun, Weilin, Zhang, Hongwen, Ou, Ning, Chen, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585954/
https://www.ncbi.nlm.nih.gov/pubmed/22339483
http://dx.doi.org/10.2165/11599330-000000000-00000

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