Hypoxia and Hypoxia Mimetics Decrease Aquaporin 5 (AQP5) Expression through Both Hypoxia Inducible Factor-1α and Proteasome-Mediated Pathways

The alveolar epithelium plays a central role in gas exchange and fluid transport, and is therefore critical for normal lung function. Since the bulk of water flux across this epithelium depends on the membrane water channel Aquaporin 5 (AQP5), we asked whether hypoxia had any effect on AQP5 expressi...

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Detalles Bibliográficos
Autores principales: Kawedia, Jitesh D., Yang, Fan, Sartor, Maureen A., Gozal, David, Czyzyk-Krzeska, Maria, Menon, Anil G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586073/
https://www.ncbi.nlm.nih.gov/pubmed/23469202
http://dx.doi.org/10.1371/journal.pone.0057541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586073/
https://www.ncbi.nlm.nih.gov/pubmed/23469202
http://dx.doi.org/10.1371/journal.pone.0057541

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