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Acute and chronic inflammatory responses induced by smoking in individuals susceptible and non-susceptible to development of COPD: from specific disease phenotyping towards novel therapy. Protocol of a cross-sectional study

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with pulmonary and extra-pulmonary manifestations. Although COPD is a complex disease, diagnosis and staging are still based on simple spirometry measurements. Different COPD phenotypes exist based on clinical, phy...

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Detalles Bibliográficos
Autores principales: Lo Tam Loi, Adèle T, Hoonhorst, Susan J M, Franciosi, Lorenza, Bischoff, Rainer, Hoffmann, Roland F, Heijink, Irene, van Oosterhout, Antoon J M, Boezen, H Marike, Timens, Wim, Postma, Dirkje S, Lammers, Jan-Willem, Koenderman, Leo, ten Hacken, Nick H T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586075/
https://www.ncbi.nlm.nih.gov/pubmed/23377993
http://dx.doi.org/10.1136/bmjopen-2012-002178