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L-Asparaginase-Induced Pancreatic Injury is Associated with an Imbalance in Plasma Amino Acid Levels

BACKGROUND: The use of L-asparaginase (ASNase) to modify amino acid metabolism is one of the most effective chemotherapeutic means of inducing remission in acute lymphoblastic leukemia (ALL). However, severe pancreatitis sometimes occurs in patients receiving ASNase, because of an unknown mechanism....

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Detalles Bibliográficos
Autores principales: Minowa, Kei, Suzuki, Mitsuyoshi, Fujimura, Junya, Saito, Masahiro, Koh, Katsuyoshi, Kikuchi, Akira, Hanada, Ryoji, Shimizu, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586115/
https://www.ncbi.nlm.nih.gov/pubmed/22594522
http://dx.doi.org/10.2165/11632990-000000000-00000

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