Cargando…

Cardiovascular Safety of Anagrelide in Healthy Subjects: Effects of Caffeine and Food Intake on Pharmacokinetics and Adverse Reactions

BACKGROUND: Essential thrombocythaemia (ET) is a rare clonal myeloproliferative disorder characterized by a sustained elevation in platelet count and megakaryocyte hyperplasia. Anagrelide is used in the treatment of ET, where it has been shown to reduce platelet count. Anagrelide is metabolized by c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martínez-Sellés, Manuel, Datino, Tomás, Figueiras-Graillet, Lourdes, Gama, Joubert G., Jones, Christopher, Franklin, Richard, Fernández-Avilés, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing AG 2012
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586167/ https://www.ncbi.nlm.nih.gov/pubmed/23184666 http://dx.doi.org/10.1007/s40261-012-0032-2

Ejemplares similares

New-onset atrial fibrillation and prognosis in nonagenarians after acute myocardial infarction
por: Martínez-Sellés, M., et al.
Publicado: (2013)

Pharmacokinetics of a Novel Anagrelide Extended‐Release Formulation in Healthy Subjects: Food Intake and Comparison With a Reference Product
por: Petrides, Petro E., et al.
Publicado: (2017)

Leg Ulcers Associated with Anagrelide
por: Oskay, Tuba, et al.
Publicado: (2021)

Cáncer y cardiotoxicidad en la población transgénero
por: Figueiras-Graillet, Lourdes M.
Publicado: (2023)

End-of-life care in a cardiology department: have we improved?
por: Ruiz-Garcia, Juan, et al.
Publicado: (2016)

The Use of Anagrelide in Myeloproliferative Neoplasms, with Focus on Essential Thrombocythemia
por: Birgegård, Gunnar
Publicado: (2016)

Anagrelide-Induced Supraventricular Tachycardia: A Case Report
por: Badar, Faraz, et al.
Publicado: (2022)

Cardiovascular Safety of Anagrelide Hydrochloride versus Hydroxyurea in Essential Thrombocythaemia
por: Gotic, Mirjana, et al.
Publicado: (2020)

Anagrelide‐induced pericardial effusion in a patient with essential thrombocythemia
por: Song, David, et al.
Publicado: (2023)

Sustained Regression of Hydroxycarbamide Induced Actinic Keratoses after Switching to Anagrelide
por: Gaitanis, Georgios, et al.
Publicado: (2018)

Anagrelide Modulates Proplatelet Formation Resulting in Decreased Number and Increased Size of Platelets
por: Miyashita, Naohiro, et al.
Publicado: (2019)

Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson’s Disease
por: Kumar, Prakash M., et al.
Publicado: (2015)

Development and Validation of a Stability-Indicating RP-HPLC Method for the Quantitative Analysis of Anagrelide Hydrochloride
por: Pujeri, Sudhakar S., et al.
Publicado: (2012)

Increased Intake of Both Caffeine and Non-Caffeine Coffee Components Is Associated with Reduced NAFLD Severity in Subjects with Type 2 Diabetes
por: Coelho, Margarida, et al.
Publicado: (2022)

Pharmacokinetics of Caffeine following a Single Administration of Coffee Enema versus Oral Coffee Consumption in Healthy Male Subjects
por: Teekachunhatean, Supanimit, et al.
Publicado: (2013)

Pharmacokinetic Interaction of Chrysin with Caffeine in Rats
por: Noh, Keumhan, et al.
Publicado: (2016)

Pharmacokinetics and Pharmacodynamics of (S)-Ketoprofen Co-Administered with Caffeine: A Preclinical Study in Arthritic Rats
por: Medina-López, Raúl, et al.
Publicado: (2018)

Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects
por: Yamazaki, Takao, et al.
Publicado: (2016)

Caffeine Intake Among Adolescents in Delhi
por: Gera, Mridul, et al.
Publicado: (2016)

TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders
por: Palmblad, Jan, et al.
Publicado: (2008)

Anagrelide-associated Cardiomyopathy and Heart Failure in a Patient with Essential Thrombocythemia: A Case Report and Literature Review
por: Sugawara, Masafumi, et al.
Publicado: (2022)

Caffeine intake interacts with Asian gene variants in Parkinson's disease: a study in 4488 subjects
por: Ong, Yi-Lin, et al.
Publicado: (2023)

Evaluation of macular and peripapillary vascular parameter change in healthy subjects after caffeine intake using optical coherence tomography angiography
por: Yilmaz Tugan, Busra, et al.
Publicado: (2022)

Effects of Baicalin on Oral Pharmacokinetics of Caffeine in Rats
por: Noh, Keumhan, et al.
Publicado: (2015)

Time effect of rutaecarpine on caffeine pharmacokinetics in rats
por: Estari, Rohit Kumar, et al.
Publicado: (2021)

Development of acute myocardial infarction in a young female patient with essential thrombocythemia treated with anagrelide: a case report
por: Lim, Young-Hyo, et al.
Publicado: (2010)

Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study
por: Giontella, Alice, et al.
Publicado: (2023)

Rhabdomyolysis from Resistance Exercise and Caffeine Intake
por: SUNG, Dong Jun, et al.
Publicado: (2018)

Time to Recover From Daily Caffeine Intake
por: Lin, Yu-Shiuan, et al.
Publicado: (2022)

Caffeine Intake and Mental Health in College Students
por: Bertasi, Raphael A. O, et al.
Publicado: (2021)

The characteristics of caffeine intake in Croatian university students
por: Laslo, D, et al.
Publicado: (2022)

A Randomized, Two-Way Crossover Study to Evaluate the Pharmacokinetics of Caffeine Delivered Using Caffeinated Chewing Gum Versus a Marketed Caffeinated Beverage in Healthy Adult Volunteers
por: Sadek, Paul, et al.
Publicado: (2017)

Inconsistency in the Ergogenic Effect of Caffeine in Athletes Who Regularly Consume Caffeine: Is It Due to the Disparity in the Criteria That Defines Habitual Caffeine Intake?
por: Filip, Aleksandra, et al.
Publicado: (2020)

Acute effects of caffeine and glucose intake on retinal vessel calibres in healthy volunteers
por: Gin, Thomas J., et al.
Publicado: (2022)

Assessment of Pharmacokinetic Interactions Between Obeticholic Acid and Caffeine, Midazolam, Warfarin, Dextromethorphan, Omeprazole, Rosuvastatin, and Digoxin in Phase 1 Studies in Healthy Subjects
por: Edwards, Jeffrey E., et al.
Publicado: (2017)

Safety and efficacy of anagrelide in Japanese post-marketing surveillance, with subgroup analyses on the effect of previous cytoreductive therapies, age, and starting dose
por: Komatsu, Norio, et al.
Publicado: (2022)

Is Caffeine Intake Associated With Urinary Incontinence in Japanese Adults?
por: Hirayama, Fumi, et al.
Publicado: (2012)

Caffeine Intake During Pregnancy and Neonatal Anthropometric Parameters
por: Wierzejska, Regina, et al.
Publicado: (2019)

The Relationship Between Caffeine Intake and Dry Eye Disease
por: Magno, Morten Schjerven, et al.
Publicado: (2023)

Sex differences in pharmacokinetics predict adverse drug reactions in women
por: Zucker, Irving, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sqqrb1o2plfilm5vaptkh0q5ll