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Invasive 3-Dimensional Organotypic Neoplasia from Multiple Normal Human Epithelia

Refined cancer models are required to assess the burgeoning number of potential targets for cancer therapeutics within a rapid and clinically relevant context. Here we utilize tumor-associated genetic pathways to transform primary human epithelial cells from epidermis, oropharynx, esophagus, and cer...

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Detalles Bibliográficos
Autores principales: Ridky, Todd W., Chow, Jennifer M., Wong, David J., Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586217/
https://www.ncbi.nlm.nih.gov/pubmed/21102459
http://dx.doi.org/10.1038/nm.2265