Sex-specific signaling through Toll-Like Receptors 2 and 4 contributes to survival outcome of Coxsackievirus B3 infection in C57Bl/6 mice

BACKGROUND: Coxsackievirus B3 (CVB3) induces myocarditis, an inflammatory heart disease, which affects men more than women. Toll-like receptor (TLR) signaling has been shown to determine the severity of CVB3-induced myocarditis. No direct role for signaling through TLR2 had been shown in myocarditis...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, Brian J, Dragon, Julie A, Moussawi, Mohamad, Huber, Sally A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586360/
https://www.ncbi.nlm.nih.gov/pubmed/23241283
http://dx.doi.org/10.1186/2042-6410-3-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586360/
https://www.ncbi.nlm.nih.gov/pubmed/23241283
http://dx.doi.org/10.1186/2042-6410-3-25

Ejemplares similares