Cargando…

IGF-1 promotes the development and cytotoxic activity of human NK cells

Insulin-like growth factor 1 (IGF-1) is a critical regulator of many physiological functions, ranging from longevity to immunity. However, little is known about the role of IGF-1 in natural killer cell development and function. Here, we identify an essential role for IGF-1 in the positive regulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ni, Fang, Sun, Rui, Fu, Binqing, Wang, Fuyan, Guo, Chuang, Tian, Zhigang, Wei, Haiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586714/ https://www.ncbi.nlm.nih.gov/pubmed/23403580 http://dx.doi.org/10.1038/ncomms2484

Ejemplares similares

MicroRNA transcriptomes of distinct human NK cell populations identify miR-362-5p as an essential regulator of NK cell function
por: Ni, Fang, et al.
Publicado: (2015)

Influenza Vaccine Induces Intracellular Immune Memory of Human NK Cells
por: Dou, Yaling, et al.
Publicado: (2015)

NKp30(+) NK cells are associated with HBV control during pegylated-interferon-alpha-2b therapy of chronic hepatitis B
por: Shen, Xiaokun, et al.
Publicado: (2016)

CD11b(−)CD27(−) NK Cells Are Associated with the Progression of Lung Carcinoma
por: Jin, Jing, et al.
Publicado: (2013)

TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence
por: Sun, Cheng, et al.
Publicado: (2012)

Human-Induced CD49a(+) NK Cells Promote Fetal Growth
por: Du, Xianghui, et al.
Publicado: (2022)

A long noncoding RNA positively regulates CD56 in human natural killer cells
por: Zhang, Ruya, et al.
Publicado: (2016)

Development of Murine Hepatic NK Cells during Ontogeny: Comparison with Spleen NK Cells
por: Wu, Xian, et al.
Publicado: (2012)

Cytokine-Based Generation of CD49a(+)Eomes(−/+) Natural Killer Cell Subsets
por: Ni, Xiang, et al.
Publicado: (2018)

Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling
por: Wang, Dongyao, et al.
Publicado: (2019)

Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19
por: Guo, Chuang, et al.
Publicado: (2022)

CD3(bright)CD56(+) T cells associate with pegylated interferon-alpha treatment nonresponse in chronic hepatitis B patients
por: Guo, Chuang, et al.
Publicado: (2016)

KIR3DS1/HLA-B Bw4-80Ile Genotype Is Correlated with the IFN-α Therapy Response in hepatitis B e antigen-Positive Chronic Hepatitis B
por: Li, Wenting, et al.
Publicado: (2017)

Immunomodulation Induced During Interferon-α Therapy Impairs the Anti-HBV Immune Response Through CD24(+)CD38(hi) B Cells
por: Fu, Binqing, et al.
Publicado: (2020)

All‐trans retinoic acid induces leukemia resistance to NK cell cytotoxicity by down‐regulating B7‐H6 expression via c‐Myc signaling
por: Cao, Guoshuai, et al.
Publicado: (2021)

Restoration of HBV-specific CD8(+) T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy
por: Wang, Dongyao, et al.
Publicado: (2021)

GARP-mediated active TGF-β1 induces bone marrow NK cell dysfunction in AML patients with early relapse post–allo-HSCT
por: Wang, Dongyao, et al.
Publicado: (2022)

Rapamycin Pretreatment Rescues the Bone Marrow AML Cell Elimination Capacity of CAR-T Cells
por: Nian, Zhigang, et al.
Publicado: (2021)

Blockade of checkpoint receptor PVRIG unleashes anti-tumor immunity of NK cells in murine and human solid tumors
por: Li, Yangyang, et al.
Publicado: (2021)

Programmed differentiated natural killer cells kill leukemia cells by engaging SLAM family receptors
por: Wu, Yang, et al.
Publicado: (2017)

Immunogenic senescence sensitizes lung cancer to LUNX-targeting therapy
por: Jiao, Defeng, et al.
Publicado: (2021)

Interactions between driver genes shape the signaling pathway landscape and direct hepatocellular carcinoma therapy
por: Shen, Yiqing, et al.
Publicado: (2023)

Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients
por: Jin, Linlin, et al.
Publicado: (2021)

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients
por: Zhou, Yonggang, et al.
Publicado: (2020)

CRACC-CRACC Interaction between Kupffer and NK Cells Contributes to Poly I:C/D-GalN Induced Hepatitis
por: Li, Yangxi, et al.
Publicado: (2013)

Why tocilizumab could be an effective treatment for severe COVID-19?
por: Fu, Binqing, et al.
Publicado: (2020)

Advances in Immunotherapy for Hepatitis B
por: Wang, Dongyao, et al.
Publicado: (2022)

IL-6 modulation for COVID-19: the right patients at the right time?
por: Ascierto, Paolo Antonio, et al.
Publicado: (2021)

TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality
por: Persyn, Eva, et al.
Publicado: (2022)

Overexpression of PTPRN Promotes Metastasis of Lung Adenocarcinoma and Suppresses NK Cell Cytotoxicity
por: Song, Xinyue, et al.
Publicado: (2021)

Technical advances in NK cell-based cellular immunotherapy
por: Fang, Fang, et al.
Publicado: (2019)

NK Cell Exhaustion
por: Bi, Jiacheng, et al.
Publicado: (2017)

LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia
por: Wang, Dong, et al.
Publicado: (2023)

Characterization of Surface Receptor Expression and Cytotoxicity of Human NK Cells and NK Cell Subsets in Overweight and Obese Humans
por: Naujoks, Wiebke, et al.
Publicado: (2020)

Low-dose immunogenic chemotherapeutics promotes immune checkpoint blockade in microsatellite stability colon cancer
por: Fang, Yuhang, et al.
Publicado: (2022)

NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing
por: Hsu, Hsiang-Ting, et al.
Publicado: (2016)

Tumor-infiltrating platelets promote the growth of lung adenocarcinoma
por: Li, Xiaohui, et al.
Publicado: (2023)

Chronic Alcohol Consumption Promotes Diethylnitrosamine-Induced Hepatocarcinogenesis via Immune Disturbances
por: Yan, Guoxiu, et al.
Publicado: (2017)

The Adverse Impact of Tumor Microenvironment on NK-Cell
por: Hu, Ziming, et al.
Publicado: (2021)

Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids
por: Giannattasio, Ariane, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_6ckv1tvuvkksiru1v1i3mvb07d