Cargando…
The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat
OBJECTIVE(S): Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of Teucrium polium honey on the wound healing and tensile strength in rat. MATERIALS AND METHODS: Thirty-six Sprague-Dawley rats were randomly d...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586860/ https://www.ncbi.nlm.nih.gov/pubmed/23493667 |
_version_ | 1782261360127639552 |
---|---|
author | Alizadeh, Ali Mohammad Sohanaki, Hamid Khaniki, Mahmod Mohaghgheghi, Mohammad Ali Ghmami, Giti Mosavi, Maryamsadat |
author_facet | Alizadeh, Ali Mohammad Sohanaki, Hamid Khaniki, Mahmod Mohaghgheghi, Mohammad Ali Ghmami, Giti Mosavi, Maryamsadat |
author_sort | Alizadeh, Ali Mohammad |
collection | PubMed |
description | OBJECTIVE(S): Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of Teucrium polium honey on the wound healing and tensile strength in rat. MATERIALS AND METHODS: Thirty-six Sprague-Dawley rats were randomly divided into four equal (n= 9) treatment and control groups. Two full-thickness wounds were made over the dorsal thoracic region according to the incision and excision models. Animals were treated with topical Teucrium polium honey twice a day post surgery until complete healing was achieved. Histopathology and tensiometry were then studied. RESULTS: The wound healing process occurred faster in the incision model than excision ones (P< 0.05). Teucrium polium honey promoted wound contraction, closure time and tensile strength (P< 0.05). Histopathological study also showed relative epithelial proliferation, improved angiogenesis granulation, and fibrous connective tissue in Teucrium polium honey treated animals. CONCLUSION: The present study demonstrates that Teucrium polium honey can accelerate wound healing as well as tensile strength in rat skin wounds. |
format | Online Article Text |
id | pubmed-3586860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-35868602013-03-14 The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat Alizadeh, Ali Mohammad Sohanaki, Hamid Khaniki, Mahmod Mohaghgheghi, Mohammad Ali Ghmami, Giti Mosavi, Maryamsadat Iran J Basic Med Sci Original Article OBJECTIVE(S): Wound healing represents a dynamic physiological process influenced by many factors. The aim of the present study was to evaluate the effects of Teucrium polium honey on the wound healing and tensile strength in rat. MATERIALS AND METHODS: Thirty-six Sprague-Dawley rats were randomly divided into four equal (n= 9) treatment and control groups. Two full-thickness wounds were made over the dorsal thoracic region according to the incision and excision models. Animals were treated with topical Teucrium polium honey twice a day post surgery until complete healing was achieved. Histopathology and tensiometry were then studied. RESULTS: The wound healing process occurred faster in the incision model than excision ones (P< 0.05). Teucrium polium honey promoted wound contraction, closure time and tensile strength (P< 0.05). Histopathological study also showed relative epithelial proliferation, improved angiogenesis granulation, and fibrous connective tissue in Teucrium polium honey treated animals. CONCLUSION: The present study demonstrates that Teucrium polium honey can accelerate wound healing as well as tensile strength in rat skin wounds. Mashhad University of Medical Sciences 2011 /pmc/articles/PMC3586860/ /pubmed/23493667 Text en © 2011: Iranian Journal of Basic Medical Sciences This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Alizadeh, Ali Mohammad Sohanaki, Hamid Khaniki, Mahmod Mohaghgheghi, Mohammad Ali Ghmami, Giti Mosavi, Maryamsadat The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat |
title | The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat |
title_full | The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat |
title_fullStr | The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat |
title_full_unstemmed | The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat |
title_short | The Effect of Teucrium Polium Hney on the Wound Healing and Tensile Strength in Rat |
title_sort | effect of teucrium polium hney on the wound healing and tensile strength in rat |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586860/ https://www.ncbi.nlm.nih.gov/pubmed/23493667 |
work_keys_str_mv | AT alizadehalimohammad theeffectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT sohanakihamid theeffectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT khanikimahmod theeffectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT mohaghgheghimohammadali theeffectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT ghmamigiti theeffectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT mosavimaryamsadat theeffectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT alizadehalimohammad effectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT sohanakihamid effectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT khanikimahmod effectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT mohaghgheghimohammadali effectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT ghmamigiti effectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat AT mosavimaryamsadat effectofteucriumpoliumhneyonthewoundhealingandtensilestrengthinrat |