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Cubic phase nanoparticles for sustained release of ibuprofen: formulation, characterization, and enhanced bioavailability study
In order to improve the oral bioavailability of ibuprofen, ibuprofen-loaded cubic nanoparticles were prepared as a delivery system for aqueous formulations. The cubic inner structure was verified by cryogenic transmission electron microscopy. With an encapsulation efficiency greater than 85%, the ib...
Autores principales: | Dian, Linghui, Yang, Zhiwen, Li, Feng, Wang, Zhouhua, Pan, Xin, Peng, Xinsheng, Huang, Xintian, Guo, Zhefei, Quan, Guilan, Shi, Xuan, Chen, Bao, Li, Ge, Wu, Chuanbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587396/ https://www.ncbi.nlm.nih.gov/pubmed/23468008 http://dx.doi.org/10.2147/IJN.S40547 |
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