Allelic Variation of the MMP3 Promoter Affects Transcription Activity through the Transcription Factor C-MYB in Human Brain Arteriovenous Malformations

MMPs comprise a family of proteolytic enzymes that degrade pericellular substances, which may result in the destabilization of vessels and related to the development of brain arteriovenous malformations (BAVM). MMP3 is a key member of this family, overexpressed in BAVM tissues, and a single nucleoti...

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Detalles Bibliográficos
Autores principales: Huai, Cong, Song, Jianping, Ma, Zengyi, Qin, Xuanfeng, Li, Peiliang, Chen, Hongyan, Zhao, Fan, Lu, Daru, Song, Donglei, Mao, Ying, Song, Xiao, Zhao, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587415/
https://www.ncbi.nlm.nih.gov/pubmed/23483952
http://dx.doi.org/10.1371/journal.pone.0057958

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