Bortezomib Reduces the Tumorigenicity of Multiple Myeloma via Downregulation of Upregulated Targets in Clonogenic Side Population Cells

Side population (SP) cells in cancers, including multiple myeloma, exhibit tumor-initiating characteristics. In the present study, we isolated SP cells from human myeloma cell lines and primary tumors to detect potential therapeutic targets specifically expressed in SP cells. We found that SP cells...

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Detalles Bibliográficos
Autores principales: Nara, Miho, Teshima, Kazuaki, Watanabe, Atsushi, Ito, Mitsugu, Iwamoto, Keiko, Kitabayashi, Atsushi, Kume, Masaaki, Hatano, Yoshiaki, Takahashi, Naoto, Iida, Shinsuke, Sawada, Kenichi, Tagawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587640/
https://www.ncbi.nlm.nih.gov/pubmed/23469177
http://dx.doi.org/10.1371/journal.pone.0056954

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