The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells

Formation of apico-basal polarity in epithelial cells is crucial for both morphogenesis (e.g., cyst formation) and function (e.g., tight junction development). Atypical protein kinase C (aPKC), complexed with Par6, is considered to translocate to the apical membrane and function in epithelial cell p...

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Detalles Bibliográficos
Autores principales: Hayase, Junya, Kamakura, Sachiko, Iwakiri, Yuko, Yamaguchi, Yoshihiro, Izaki, Tomoko, Ito, Takashi, Sumimoto, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587828/
https://www.ncbi.nlm.nih.gov/pubmed/23439680
http://dx.doi.org/10.1083/jcb.201208150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587828/
https://www.ncbi.nlm.nih.gov/pubmed/23439680
http://dx.doi.org/10.1083/jcb.201208150

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