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The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells
Formation of apico-basal polarity in epithelial cells is crucial for both morphogenesis (e.g., cyst formation) and function (e.g., tight junction development). Atypical protein kinase C (aPKC), complexed with Par6, is considered to translocate to the apical membrane and function in epithelial cell p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587828/ https://www.ncbi.nlm.nih.gov/pubmed/23439680 http://dx.doi.org/10.1083/jcb.201208150 |