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Arp2/3 complex ATP hydrolysis promotes lamellipodial actin network disassembly but is dispensable for assembly

We examined the role of ATP hydrolysis by the Arp2/3 complex in building the leading edge of a cell by studying the effects of hydrolysis defects on the behavior of the complex in the lamellipodial actin network of Drosophila S2 cells and in a reconstituted, in vitro, actin-based motility system. In...

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Detalles Bibliográficos
Autores principales:	Ingerman, Elena, Hsiao, Jennifer Ying, Mullins, R. Dyche
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587832/ https://www.ncbi.nlm.nih.gov/pubmed/23439681 http://dx.doi.org/10.1083/jcb.201211069

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