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Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28

In embryonic stem cells, removal of oxidatively damaged proteins is triggered upon the first signs of cell fate specification but the underlying mechanism is not known. Here, we report that this phase of differentiation encompasses an unexpected induction of genes encoding the proteasome activator P...

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Detalles Bibliográficos
Autores principales:	Hernebring, Malin, Fredriksson, Åsa, Liljevald, Maria, Cvijovic, Marija, Norrman, Karin, Wiseman, John, Semb, Henrik, Nyström, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587881/ https://www.ncbi.nlm.nih.gov/pubmed/23459332 http://dx.doi.org/10.1038/srep01381

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