hERG channel function: beyond long QT

To date, research on the human ether-a-go-go related gene (hERG) has focused on this potassium channel's role in cardiac repolarization and Long QT Syndrome (LQTS). However, growing evidence implicates hERG in a diversity of physiologic and pathological processes. Here we discuss these other fu...

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Detalles Bibliográficos
Autores principales: Babcock, Joseph J, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587915/
https://www.ncbi.nlm.nih.gov/pubmed/23459091
http://dx.doi.org/10.1038/aps.2013.6
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author Babcock, Joseph J
Li, Min
author_facet Babcock, Joseph J
Li, Min
author_sort Babcock, Joseph J
collection PubMed
description To date, research on the human ether-a-go-go related gene (hERG) has focused on this potassium channel's role in cardiac repolarization and Long QT Syndrome (LQTS). However, growing evidence implicates hERG in a diversity of physiologic and pathological processes. Here we discuss these other functions of hERG, particularly their impact on diseases beyond cardiac arrhythmia.
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spelling pubmed-35879152013-03-05 hERG channel function: beyond long QT Babcock, Joseph J Li, Min Acta Pharmacol Sin Perspective To date, research on the human ether-a-go-go related gene (hERG) has focused on this potassium channel's role in cardiac repolarization and Long QT Syndrome (LQTS). However, growing evidence implicates hERG in a diversity of physiologic and pathological processes. Here we discuss these other functions of hERG, particularly their impact on diseases beyond cardiac arrhythmia. Nature Publishing Group 2013-03 2013-03-05 /pmc/articles/PMC3587915/ /pubmed/23459091 http://dx.doi.org/10.1038/aps.2013.6 Text en Copyright © 2013 CPS and SIMM http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Perspective
Babcock, Joseph J
Li, Min
hERG channel function: beyond long QT
title hERG channel function: beyond long QT
title_full hERG channel function: beyond long QT
title_fullStr hERG channel function: beyond long QT
title_full_unstemmed hERG channel function: beyond long QT
title_short hERG channel function: beyond long QT
title_sort herg channel function: beyond long qt
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587915/
https://www.ncbi.nlm.nih.gov/pubmed/23459091
http://dx.doi.org/10.1038/aps.2013.6
work_keys_str_mv AT babcockjosephj hergchannelfunctionbeyondlongqt
AT limin hergchannelfunctionbeyondlongqt

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