Chemical Inhibitors and microRNAs (miRNA) Targeting the Mammalian Target of Rapamycin (mTOR) Pathway: Potential for Novel Anticancer Therapeutics

The mammalian target of rapamycin (mTOR) is a critical regulator of many fundamental features in response to upstream cellular signals, such as growth factors, energy, stress and nutrients, controlling cell growth, proliferation and metabolism through two complexes, mTORC1 and mTORC2. Dysregulation...

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Detalles Bibliográficos
Autores principales: AlQurashi, Naif, Hashimi, Saeed M., Wei, Ming Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588076/
https://www.ncbi.nlm.nih.gov/pubmed/23434669
http://dx.doi.org/10.3390/ijms14023874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588076/
https://www.ncbi.nlm.nih.gov/pubmed/23434669
http://dx.doi.org/10.3390/ijms14023874

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