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Remarkable Role of Indoleamine 2,3-Dioxygenase and Tryptophan Metabolites in Infectious Diseases: Potential Role in Macrophage-Mediated Inflammatory Diseases

Indoleamine 2,3-dioxygenase 1 (IDO1), the L-tryptophan-degrading enzyme, plays a key role in the immunomodulatory effects on several types of immune cells. Originally known for its regulatory function during pregnancy and chronic inflammation in tumorigenesis, the activity of IDO1 seems to modify th...

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Detalles Bibliográficos
Autores principales:	Murakami, Yuki, Hoshi, Masato, Imamura, Yukio, Arioka, Yuko, Yamamoto, Yasuko, Saito, Kuniaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588179/ https://www.ncbi.nlm.nih.gov/pubmed/23476103 http://dx.doi.org/10.1155/2013/391984

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