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Cinnarizinium fumarate
In the title salt {systematic name: 4-diphenylmethyl-1-[(E)-3-phenylprop-2-en-1-yl]piperazin-1-ium (2Z)-3-carboxyprop-2-enoate}, C(26)H(29)N(2) (+)·C(4)H(3)O(4) (−), the piperazine ring in the cation adopts a distorted chair conformation and contains a positively charged N atom with quaternary c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588249/ https://www.ncbi.nlm.nih.gov/pubmed/23476398 http://dx.doi.org/10.1107/S1600536812051239 |
Sumario: | In the title salt {systematic name: 4-diphenylmethyl-1-[(E)-3-phenylprop-2-en-1-yl]piperazin-1-ium (2Z)-3-carboxyprop-2-enoate}, C(26)H(29)N(2) (+)·C(4)H(3)O(4) (−), the piperazine ring in the cation adopts a distorted chair conformation and contains a positively charged N atom with quaternary character. The dihedral angle between the mean planes of the phenyl rings of the diphenylmethyl group is 74.2 (7)° and those between these rings and the phenyl ring of the 3-phenylprop-2-en-1-yl group are 12.7 (9) and 80.6 (8)°. In the crystal, N—H⋯O and O—H⋯O hydrogen bonds form chains along [001]. Weak C—H⋯O interactions connect parallel chains along [010], forming layers perpendicular to the a-axis direction. |
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