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4-Cyano-N-ethyl­spiro­[chromene-2,4′-piperidine]-1′-carboxamide

The title compound, C(17)H(19)N(3)O(2), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. In both mol­ecules, the pyran ring has a twisted conformation ((5) S (4)), with Q = 0.301 (3) Å, θ = 116.7 (6) and ϕ= 213.6 (7)° for mol­ecule A, and Q = 0.364 (2) Å, θ = 113.7 (3)...

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Detalles Bibliográficos
Autores principales: Rajalakshmi, P., Srinivasan, N., Krishnakumar, R. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588295/
https://www.ncbi.nlm.nih.gov/pubmed/23476394
http://dx.doi.org/10.1107/S1600536812051124
Descripción
Sumario:The title compound, C(17)H(19)N(3)O(2), crystallizes with two independent mol­ecules (A and B) in the asymmetric unit. In both mol­ecules, the pyran ring has a twisted conformation ((5) S (4)), with Q = 0.301 (3) Å, θ = 116.7 (6) and ϕ= 213.6 (7)° for mol­ecule A, and Q = 0.364 (2) Å, θ = 113.7 (3) and ϕ = 213.0 (4)° for mol­ecule B. In mol­ecule B, the terminal ethyl group is disordered over two orientations with an occupancy ratio of 0.55 (1):0.45 (1). In the crystal, mol­ecules A and B form very similar but separate R (1) (2)(7) motifs through N—H⋯O and C—H⋯O hydrogen bonds. The resulting chains along [001] are inter­linked by weaker C—H⋯O and C—H⋯π inter­actions, forming layers parallel to the bc plane.