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4-Cyano-N-ethylspiro[chromene-2,4′-piperidine]-1′-carboxamide
The title compound, C(17)H(19)N(3)O(2), crystallizes with two independent molecules (A and B) in the asymmetric unit. In both molecules, the pyran ring has a twisted conformation ((5) S (4)), with Q = 0.301 (3) Å, θ = 116.7 (6) and ϕ= 213.6 (7)° for molecule A, and Q = 0.364 (2) Å, θ = 113.7 (3)...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588295/ https://www.ncbi.nlm.nih.gov/pubmed/23476394 http://dx.doi.org/10.1107/S1600536812051124 |
Sumario: | The title compound, C(17)H(19)N(3)O(2), crystallizes with two independent molecules (A and B) in the asymmetric unit. In both molecules, the pyran ring has a twisted conformation ((5) S (4)), with Q = 0.301 (3) Å, θ = 116.7 (6) and ϕ= 213.6 (7)° for molecule A, and Q = 0.364 (2) Å, θ = 113.7 (3) and ϕ = 213.0 (4)° for molecule B. In molecule B, the terminal ethyl group is disordered over two orientations with an occupancy ratio of 0.55 (1):0.45 (1). In the crystal, molecules A and B form very similar but separate R (1) (2)(7) motifs through N—H⋯O and C—H⋯O hydrogen bonds. The resulting chains along [001] are interlinked by weaker C—H⋯O and C—H⋯π interactions, forming layers parallel to the bc plane. |
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