Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate

In the title mol­ecule, C(24)H(28)N(2)O(3), the cyclo­hexene ring is in a sofa conformation and the 1,4-dihydro­pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63 (7)°. In the crystal, N—H⋯O hydrogen bonds connect th...

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Detalles Bibliográficos
Autores principales: Öztürk Yildirim, Sema, Butcher, Ray J., Gündüz, Miyase Gözde, El-Khouly, Ahmed, Şimşek, Rahime, Şafak, Cihat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588325/
https://www.ncbi.nlm.nih.gov/pubmed/23476426
http://dx.doi.org/10.1107/S1600536812047976
Descripción
Sumario:In the title mol­ecule, C(24)H(28)N(2)O(3), the cyclo­hexene ring is in a sofa conformation and the 1,4-dihydro­pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63 (7)°. In the crystal, N—H⋯O hydrogen bonds connect the mol­ecules into C(6) chains parallel to the b axis and pairs of weak C—H⋯O hydrogen bonds link inversion-related chains into a ladder motif through R (2) (2)(18) rings. A weak intra­molecular C—H⋯O hydrogen bond is also observed.

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