Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate

In the title mol­ecule, C(24)H(28)N(2)O(3), the cyclo­hexene ring is in a sofa conformation and the 1,4-dihydro­pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63 (7)°. In the crystal, N—H⋯O hydrogen bonds connect th...

Descripción completa

Detalles Bibliográficos
Autores principales: Öztürk Yildirim, Sema, Butcher, Ray J., Gündüz, Miyase Gözde, El-Khouly, Ahmed, Şimşek, Rahime, Şafak, Cihat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588325/
https://www.ncbi.nlm.nih.gov/pubmed/23476426
http://dx.doi.org/10.1107/S1600536812047976
_version_ 1782261539875586048
author Öztürk Yildirim, Sema
Butcher, Ray J.
Gündüz, Miyase Gözde
El-Khouly, Ahmed
Şimşek, Rahime
Şafak, Cihat
author_facet Öztürk Yildirim, Sema
Butcher, Ray J.
Gündüz, Miyase Gözde
El-Khouly, Ahmed
Şimşek, Rahime
Şafak, Cihat
author_sort Öztürk Yildirim, Sema
collection PubMed
description In the title mol­ecule, C(24)H(28)N(2)O(3), the cyclo­hexene ring is in a sofa conformation and the 1,4-dihydro­pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63 (7)°. In the crystal, N—H⋯O hydrogen bonds connect the mol­ecules into C(6) chains parallel to the b axis and pairs of weak C—H⋯O hydrogen bonds link inversion-related chains into a ladder motif through R (2) (2)(18) rings. A weak intra­molecular C—H⋯O hydrogen bond is also observed.
format Online
Article
Text
id pubmed-3588325
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-35883252013-03-08 Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate Öztürk Yildirim, Sema Butcher, Ray J. Gündüz, Miyase Gözde El-Khouly, Ahmed Şimşek, Rahime Şafak, Cihat Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title mol­ecule, C(24)H(28)N(2)O(3), the cyclo­hexene ring is in a sofa conformation and the 1,4-dihydro­pyridine ring is in a slight boat conformation. In the indole ring system, the pyrrole and benzene rings form a dihedral angle of 2.63 (7)°. In the crystal, N—H⋯O hydrogen bonds connect the mol­ecules into C(6) chains parallel to the b axis and pairs of weak C—H⋯O hydrogen bonds link inversion-related chains into a ladder motif through R (2) (2)(18) rings. A weak intra­molecular C—H⋯O hydrogen bond is also observed. International Union of Crystallography 2012-12-08 /pmc/articles/PMC3588325/ /pubmed/23476426 http://dx.doi.org/10.1107/S1600536812047976 Text en © Öztürk Yildirim et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Öztürk Yildirim, Sema
Butcher, Ray J.
Gündüz, Miyase Gözde
El-Khouly, Ahmed
Şimşek, Rahime
Şafak, Cihat
Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
title Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
title_full Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
title_fullStr Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
title_full_unstemmed Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
title_short Ethyl 2,7,7-trimethyl-4-(1-methyl-1H-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
title_sort ethyl 2,7,7-trimethyl-4-(1-methyl-1h-indol-3-yl)-5-oxo-1,4,5,6,7,8-hexa­hydro­quinoline-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588325/
https://www.ncbi.nlm.nih.gov/pubmed/23476426
http://dx.doi.org/10.1107/S1600536812047976
work_keys_str_mv AT ozturkyildirimsema ethyl277trimethyl41methyl1hindol3yl5oxo145678hexahydroquinoline3carboxylate
AT butcherrayj ethyl277trimethyl41methyl1hindol3yl5oxo145678hexahydroquinoline3carboxylate
AT gunduzmiyasegozde ethyl277trimethyl41methyl1hindol3yl5oxo145678hexahydroquinoline3carboxylate
AT elkhoulyahmed ethyl277trimethyl41methyl1hindol3yl5oxo145678hexahydroquinoline3carboxylate
AT simsekrahime ethyl277trimethyl41methyl1hindol3yl5oxo145678hexahydroquinoline3carboxylate
AT safakcihat ethyl277trimethyl41methyl1hindol3yl5oxo145678hexahydroquinoline3carboxylate

Ejemplares similares