3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one

The title compound, C(13)H(17)NO(3), adopts a conformation in which the aromatic ring and the mean plane of the piperidine ring are almost perpendicular to each other [dihedral angle = 79.25 (6)°]. The presence of the carbonyl group alters the conformation of the piperidine ring from a chair to a tw...

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Detalles Bibliográficos
Autores principales: Pienaar, Daniel P., Khorasani, Sanaz, de Koning, Charles B., Michael, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588348/
https://www.ncbi.nlm.nih.gov/pubmed/23476435
http://dx.doi.org/10.1107/S1600536812049501
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author Pienaar, Daniel P.
Khorasani, Sanaz
de Koning, Charles B.
Michael, Joseph P.
author_facet Pienaar, Daniel P.
Khorasani, Sanaz
de Koning, Charles B.
Michael, Joseph P.
author_sort Pienaar, Daniel P.
collection PubMed
description The title compound, C(13)H(17)NO(3), adopts a conformation in which the aromatic ring and the mean plane of the piperidine ring are almost perpendicular to each other [dihedral angle = 79.25 (6)°]. The presence of the carbonyl group alters the conformation of the piperidine ring from a chair to a twisted half-chair conformation. In the crystal, pairs of strong O—H⋯O hydrogen bonds link the mol­ecules into inversion dimers. Weak C—H⋯O inter­actions extend the hydrogen-bonding network into three dimensions.
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spelling pubmed-35883482013-03-08 3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one Pienaar, Daniel P. Khorasani, Sanaz de Koning, Charles B. Michael, Joseph P. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(13)H(17)NO(3), adopts a conformation in which the aromatic ring and the mean plane of the piperidine ring are almost perpendicular to each other [dihedral angle = 79.25 (6)°]. The presence of the carbonyl group alters the conformation of the piperidine ring from a chair to a twisted half-chair conformation. In the crystal, pairs of strong O—H⋯O hydrogen bonds link the mol­ecules into inversion dimers. Weak C—H⋯O inter­actions extend the hydrogen-bonding network into three dimensions. International Union of Crystallography 2012-12-08 /pmc/articles/PMC3588348/ /pubmed/23476435 http://dx.doi.org/10.1107/S1600536812049501 Text en © Pienaar et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Pienaar, Daniel P.
Khorasani, Sanaz
de Koning, Charles B.
Michael, Joseph P.
3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
title 3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
title_full 3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
title_fullStr 3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
title_full_unstemmed 3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
title_short 3-Hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
title_sort 3-hy­droxy-1-(4-meth­oxy­benz­yl)piperidin-2-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588348/
https://www.ncbi.nlm.nih.gov/pubmed/23476435
http://dx.doi.org/10.1107/S1600536812049501
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AT dekoningcharlesb 3hydroxy14methoxybenzylpiperidin2one
AT michaeljosephp 3hydroxy14methoxybenzylpiperidin2one

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