(3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one

The title compound, C(22)H(21)Cl(2)NO, is a derivative of mono-carbonyl analogues of curcumin (MACs). The mol­ecule has an E conformation for each of the olefinic bonds. The 1-propyl­piperidin-4-one ring has a distorted chair conformation with the ring N and the C and O atoms of the carbonyl group d...

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Detalles Bibliográficos
Autores principales: Yang, Quanzhi, Chen, Lingzi, Weng, Bixia, Fan, Lei, Wu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588387/
https://www.ncbi.nlm.nih.gov/pubmed/23476444
http://dx.doi.org/10.1107/S1600536812049252
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author Yang, Quanzhi
Chen, Lingzi
Weng, Bixia
Fan, Lei
Wu, Xiaoping
author_facet Yang, Quanzhi
Chen, Lingzi
Weng, Bixia
Fan, Lei
Wu, Xiaoping
author_sort Yang, Quanzhi
collection PubMed
description The title compound, C(22)H(21)Cl(2)NO, is a derivative of mono-carbonyl analogues of curcumin (MACs). The mol­ecule has an E conformation for each of the olefinic bonds. The 1-propyl­piperidin-4-one ring has a distorted chair conformation with the ring N and the C and O atoms of the carbonyl group deviating from the mean plane of the remaining four ring C atoms by 0.682 (2), −0.134 (3) and −0.340 (4) Å, respectively. The dihedral angle between the benzene rings is 26.5 (1)°. In the crystal, mol­ecules are connected by weak C—H⋯O and C—H⋯π inter­actions.
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spelling pubmed-35883872013-03-08 (3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one Yang, Quanzhi Chen, Lingzi Weng, Bixia Fan, Lei Wu, Xiaoping Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(22)H(21)Cl(2)NO, is a derivative of mono-carbonyl analogues of curcumin (MACs). The mol­ecule has an E conformation for each of the olefinic bonds. The 1-propyl­piperidin-4-one ring has a distorted chair conformation with the ring N and the C and O atoms of the carbonyl group deviating from the mean plane of the remaining four ring C atoms by 0.682 (2), −0.134 (3) and −0.340 (4) Å, respectively. The dihedral angle between the benzene rings is 26.5 (1)°. In the crystal, mol­ecules are connected by weak C—H⋯O and C—H⋯π inter­actions. International Union of Crystallography 2012-12-08 /pmc/articles/PMC3588387/ /pubmed/23476444 http://dx.doi.org/10.1107/S1600536812049252 Text en © Yang et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yang, Quanzhi
Chen, Lingzi
Weng, Bixia
Fan, Lei
Wu, Xiaoping
(3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
title (3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
title_full (3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
title_fullStr (3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
title_full_unstemmed (3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
title_short (3E,5E)-3,5-Bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
title_sort (3e,5e)-3,5-bis(2-chloro­benzyl­idene)-1-propyl­piperidin-4-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588387/
https://www.ncbi.nlm.nih.gov/pubmed/23476444
http://dx.doi.org/10.1107/S1600536812049252
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