1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione

The title mol­ecule, C(21)H(28)O(5), is composed of three six-membered rings (A/B/C) and a five-membered ring (D). Ring A adopts a 1α-sofa conformation, while rings B and C adopt chair conformations. Cyclo­pentane ring D adopts a 14α-envelope conformation. In the crystal, O—H⋯O hydrogen bonds lead t...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yan-Bing, Wang, Yi-Bo, Luo, Jian-Mei, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588417/
https://www.ncbi.nlm.nih.gov/pubmed/23476615
http://dx.doi.org/10.1107/S1600536813005023
_version_ 1782261561000198144
author Shen, Yan-Bing
Wang, Yi-Bo
Luo, Jian-Mei
Wang, Min
author_facet Shen, Yan-Bing
Wang, Yi-Bo
Luo, Jian-Mei
Wang, Min
author_sort Shen, Yan-Bing
collection PubMed
description The title mol­ecule, C(21)H(28)O(5), is composed of three six-membered rings (A/B/C) and a five-membered ring (D). Ring A adopts a 1α-sofa conformation, while rings B and C adopt chair conformations. Cyclo­pentane ring D adopts a 14α-envelope conformation. In the crystal, O—H⋯O hydrogen bonds lead to the formation of ribbons running along the a axis. The structure is further consolidated by C—H⋯O inter­actions, which link the molecules head-to-tail into ribbons along the a axis.
format Online
Article
Text
id pubmed-3588417
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-35884172013-03-08 1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione Shen, Yan-Bing Wang, Yi-Bo Luo, Jian-Mei Wang, Min Acta Crystallogr Sect E Struct Rep Online Organic Papers The title mol­ecule, C(21)H(28)O(5), is composed of three six-membered rings (A/B/C) and a five-membered ring (D). Ring A adopts a 1α-sofa conformation, while rings B and C adopt chair conformations. Cyclo­pentane ring D adopts a 14α-envelope conformation. In the crystal, O—H⋯O hydrogen bonds lead to the formation of ribbons running along the a axis. The structure is further consolidated by C—H⋯O inter­actions, which link the molecules head-to-tail into ribbons along the a axis. International Union of Crystallography 2013-02-28 /pmc/articles/PMC3588417/ /pubmed/23476615 http://dx.doi.org/10.1107/S1600536813005023 Text en © Shen et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Shen, Yan-Bing
Wang, Yi-Bo
Luo, Jian-Mei
Wang, Min
1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
title 1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
title_full 1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
title_fullStr 1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
title_full_unstemmed 1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
title_short 1β,15α-Dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
title_sort 1β,15α-dihy­droxy-16α,17-ep­oxy­pregn-4-ene-3,20-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588417/
https://www.ncbi.nlm.nih.gov/pubmed/23476615
http://dx.doi.org/10.1107/S1600536813005023
work_keys_str_mv AT shenyanbing 1b15adihydroxy16a17epoxypregn4ene320dione
AT wangyibo 1b15adihydroxy16a17epoxypregn4ene320dione
AT luojianmei 1b15adihydroxy16a17epoxypregn4ene320dione
AT wangmin 1b15adihydroxy16a17epoxypregn4ene320dione

Ejemplares similares