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2-[N-(4-Methoxyphenyl)acetamido]-1,3-thiazol-4-yl acetate
The structural analysis of the title compound, C(14)H(14)N(2)O(4)S, particularly the presence of an acetyl group at the exocyclic N atom and the C(H)—C(O(2)CMe)—N acetoxy group in the thiazole ring, may indicate that one of the starting materials, i.e. 2-(4-methoxyanilino)-1,3-thiazol-4(5H)-one...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588441/ https://www.ncbi.nlm.nih.gov/pubmed/23476576 http://dx.doi.org/10.1107/S1600536813004236 |
Sumario: | The structural analysis of the title compound, C(14)H(14)N(2)O(4)S, particularly the presence of an acetyl group at the exocyclic N atom and the C(H)—C(O(2)CMe)—N acetoxy group in the thiazole ring, may indicate that one of the starting materials, i.e. 2-(4-methoxyanilino)-1,3-thiazol-4(5H)-one, exists in the reaction mixture, at least partially, as a tautomer with an exocyclic amine N atom and an enol group. The acetoxy and acetyl groups deviate from the thiazole plane by 69.17 (6) and 7.25 (19)°, respectively. The thiazole and benzene rings form a dihedral angle of 73.50 (4)°. In the crystal, centrosymmetrically related molecules are connected into dimeric aggregates via C—H⋯O interactions. |
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