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2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate

The structural analysis of the title compound, C(14)H(14)N(2)O(4)S, particularly the presence of an acetyl group at the exocyclic N atom and the C(H)—C(O(2)CMe)—N acet­oxy group in the thia­zole ring, may indicate that one of the starting materials, i.e. 2-(4-meth­oxy­anilino)-1,3-thia­zol-4(5H)-one...

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Autores principales: Horishny, Volodymyr, Lesyk, Roman, Gzella, Andrzej K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588441/
https://www.ncbi.nlm.nih.gov/pubmed/23476576
http://dx.doi.org/10.1107/S1600536813004236
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author Horishny, Volodymyr
Lesyk, Roman
Gzella, Andrzej K.
author_facet Horishny, Volodymyr
Lesyk, Roman
Gzella, Andrzej K.
author_sort Horishny, Volodymyr
collection PubMed
description The structural analysis of the title compound, C(14)H(14)N(2)O(4)S, particularly the presence of an acetyl group at the exocyclic N atom and the C(H)—C(O(2)CMe)—N acet­oxy group in the thia­zole ring, may indicate that one of the starting materials, i.e. 2-(4-meth­oxy­anilino)-1,3-thia­zol-4(5H)-one, exists in the reaction mixture, at least partially, as a tautomer with an exocyclic amine N atom and an enol group. The acet­oxy and acetyl groups deviate from the thia­zole plane by 69.17 (6) and 7.25 (19)°, respectively. The thia­zole and benzene rings form a dihedral angle of 73.50 (4)°. In the crystal, centrosymmetrically related mol­ecules are connected into dimeric aggregates via C—H⋯O inter­actions.
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spelling pubmed-35884412013-03-08 2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate Horishny, Volodymyr Lesyk, Roman Gzella, Andrzej K. Acta Crystallogr Sect E Struct Rep Online Organic Papers The structural analysis of the title compound, C(14)H(14)N(2)O(4)S, particularly the presence of an acetyl group at the exocyclic N atom and the C(H)—C(O(2)CMe)—N acet­oxy group in the thia­zole ring, may indicate that one of the starting materials, i.e. 2-(4-meth­oxy­anilino)-1,3-thia­zol-4(5H)-one, exists in the reaction mixture, at least partially, as a tautomer with an exocyclic amine N atom and an enol group. The acet­oxy and acetyl groups deviate from the thia­zole plane by 69.17 (6) and 7.25 (19)°, respectively. The thia­zole and benzene rings form a dihedral angle of 73.50 (4)°. In the crystal, centrosymmetrically related mol­ecules are connected into dimeric aggregates via C—H⋯O inter­actions. International Union of Crystallography 2013-02-16 /pmc/articles/PMC3588441/ /pubmed/23476576 http://dx.doi.org/10.1107/S1600536813004236 Text en © Horishny et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Horishny, Volodymyr
Lesyk, Roman
Gzella, Andrzej K.
2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
title 2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
title_full 2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
title_fullStr 2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
title_full_unstemmed 2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
title_short 2-[N-(4-Meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
title_sort 2-[n-(4-meth­oxy­phen­yl)acetamido]-1,3-thia­zol-4-yl acetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588441/
https://www.ncbi.nlm.nih.gov/pubmed/23476576
http://dx.doi.org/10.1107/S1600536813004236
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