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The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables
Exercise is one of the most powerful non-pharmacological strategies, which can affect nearly all cells and organs in the body. Changes in the behavior of adult stem cells have been shown to occur in response to exercise. Exercise may act on regenerative potential of tissues by altering the ability t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Akademia Wychowania Fizycznego w Katowicach
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588690/ https://www.ncbi.nlm.nih.gov/pubmed/23486555 http://dx.doi.org/10.2478/v10078-012-0080-y |
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author | Shalaby, Mohammed Nader Saad, Mohammed Akar, Samy Reda, Mubarak Abdelreda Ali Shalgham, Ahmed |
author_facet | Shalaby, Mohammed Nader Saad, Mohammed Akar, Samy Reda, Mubarak Abdelreda Ali Shalgham, Ahmed |
author_sort | Shalaby, Mohammed Nader |
collection | PubMed |
description | Exercise is one of the most powerful non-pharmacological strategies, which can affect nearly all cells and organs in the body. Changes in the behavior of adult stem cells have been shown to occur in response to exercise. Exercise may act on regenerative potential of tissues by altering the ability to generate new stem cells and differentiated cells that are able to carry out tissue specific functions. The purpose of this study was to reveal the role of aerobic and anaerobic training programs on CD34+ Stem Cells and chosen physiological variables. Twenty healthy male athletes aged 18–24 years were recruited for this study. Healthy low active males and BMI matched participants (n=10) aged 20–22 years were recruited as controls. Aerobic and anaerobic training programs for 12 weeks were conducted. VO2max pulse observation was carried out using the Astrand Rhyming protocol. RBCs, WBCs, HB and hematocrit were estimated using a coulter counter, lactate by the Accusport apparatus, CD34+ stem cells by flow cytometry. VO2max was increased significantly in case of the aerobic training program compared to anaerobic one (62±2.2 ml/kg/min vs. 54±2.1 ml/kg/min). Haemotological values increased significantly in the anaerobic program when compared to the aerobic one, RBCs (5.3±0.3 and 4.9±0.2 mln/ul), WBCs (6.6±0.5 and 6.1±0.4 thous/ul), HB (15.4±0.4 and 14.2±0.5 g/de), Hematocrit (4.6±1.2 and 4.4±1.1 %), CD34+ stem cells count increased significantly in case of the anaerobic program compared to the aerobic (251.6±21.64 and 130±14.61) and sedentary one (172±24.10). These findings suggest that anaerobic training programs provoke better adaptation to exercise and stem cell counts may differ between trained and sedentary subjects. Circulating immature cells are likely to be involved in angiogenesis and repair process, both mechanisms being associated with strenuous exercise. Knowledge of the physiological effects of training on stem cells might be of potential clinical use. |
format | Online Article Text |
id | pubmed-3588690 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Akademia Wychowania Fizycznego w Katowicach |
record_format | MEDLINE/PubMed |
spelling | pubmed-35886902013-03-13 The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables Shalaby, Mohammed Nader Saad, Mohammed Akar, Samy Reda, Mubarak Abdelreda Ali Shalgham, Ahmed J Hum Kinet Research Article Exercise is one of the most powerful non-pharmacological strategies, which can affect nearly all cells and organs in the body. Changes in the behavior of adult stem cells have been shown to occur in response to exercise. Exercise may act on regenerative potential of tissues by altering the ability to generate new stem cells and differentiated cells that are able to carry out tissue specific functions. The purpose of this study was to reveal the role of aerobic and anaerobic training programs on CD34+ Stem Cells and chosen physiological variables. Twenty healthy male athletes aged 18–24 years were recruited for this study. Healthy low active males and BMI matched participants (n=10) aged 20–22 years were recruited as controls. Aerobic and anaerobic training programs for 12 weeks were conducted. VO2max pulse observation was carried out using the Astrand Rhyming protocol. RBCs, WBCs, HB and hematocrit were estimated using a coulter counter, lactate by the Accusport apparatus, CD34+ stem cells by flow cytometry. VO2max was increased significantly in case of the aerobic training program compared to anaerobic one (62±2.2 ml/kg/min vs. 54±2.1 ml/kg/min). Haemotological values increased significantly in the anaerobic program when compared to the aerobic one, RBCs (5.3±0.3 and 4.9±0.2 mln/ul), WBCs (6.6±0.5 and 6.1±0.4 thous/ul), HB (15.4±0.4 and 14.2±0.5 g/de), Hematocrit (4.6±1.2 and 4.4±1.1 %), CD34+ stem cells count increased significantly in case of the anaerobic program compared to the aerobic (251.6±21.64 and 130±14.61) and sedentary one (172±24.10). These findings suggest that anaerobic training programs provoke better adaptation to exercise and stem cell counts may differ between trained and sedentary subjects. Circulating immature cells are likely to be involved in angiogenesis and repair process, both mechanisms being associated with strenuous exercise. Knowledge of the physiological effects of training on stem cells might be of potential clinical use. Akademia Wychowania Fizycznego w Katowicach 2012-12-30 /pmc/articles/PMC3588690/ /pubmed/23486555 http://dx.doi.org/10.2478/v10078-012-0080-y Text en © Editorial Committee of Journal of Human Kinetics http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Research Article Shalaby, Mohammed Nader Saad, Mohammed Akar, Samy Reda, Mubarak Abdelreda Ali Shalgham, Ahmed The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables |
title | The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables |
title_full | The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables |
title_fullStr | The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables |
title_full_unstemmed | The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables |
title_short | The Role of Aerobic and Anaerobic Training Programs on CD(34+) Stem Cells and Chosen Physiological Variables |
title_sort | role of aerobic and anaerobic training programs on cd(34+) stem cells and chosen physiological variables |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588690/ https://www.ncbi.nlm.nih.gov/pubmed/23486555 http://dx.doi.org/10.2478/v10078-012-0080-y |
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