Corneal Involvement in Xeroderma Pigmentosum;a Histopathologic Report

PURPOSE: To report the histopathologic features of corneal involvement in a patient with xeroderma pigmentosum (XP). CASE REPORT: A 19-year-old man with XP presented with bilateral corneal leukoma and decreased visual acuity predominatly in his right eye. Penetrating keratoplasty was performed in th...

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Detalles Bibliográficos
Autores principales: Rezaei Kanavi, Mozhgan, Javadi, Mohammad-Ali, Zabihi Yeganeh, Hamid-Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ophthalmic Research Center 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589216/
https://www.ncbi.nlm.nih.gov/pubmed/23479524
Descripción
Sumario:PURPOSE: To report the histopathologic features of corneal involvement in a patient with xeroderma pigmentosum (XP). CASE REPORT: A 19-year-old man with XP presented with bilateral corneal leukoma and decreased visual acuity predominatly in his right eye. Penetrating keratoplasty was performed in the right eye due to severe corneal opacity, vascularization and lipid deposition. The corneal button underwent histopathologic evaluation which disclosed chronic interstitial lipogranulomatous keratitis. CONCLUSION: To our knowledge, this is the first report of corneal involvement in xeroderma pigmentosum from Iran describing the histopathologic features in this rare condition.

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